:root{--ink:#132d42;--muted:#536774;--teal:#096b65;--line:#dbe4e8;--paper:#fff;--wash:#f4f7f8;--soft:#e9f4f1;--amber:#80530d;--radius:12px}
*{box-sizing:border-box}html{scroll-behavior:smooth}body{margin:0;background:var(--wash);color:var(--ink);font-family:Inter,-apple-system,BlinkMacSystemFont,"Segoe UI",sans-serif;font-size:15px;line-height:1.6}a{color:var(--teal);text-underline-offset:3px}button,input,select{font:inherit}button,a,input,select,summary{-webkit-tap-highlight-color:transparent}button{cursor:pointer}button:disabled{cursor:default;opacity:.45}:focus-visible{outline:3px solid #368ca3;outline-offset:3px}.skip{position:absolute;left:12px;top:-100px;background:#fff;padding:12px;z-index:100}.skip:focus{top:12px}.site-header{background:#fff;border-bottom:1px solid var(--line)}.site-nav{max-width:1280px;margin:auto;min-height:78px;padding:15px 32px;display:flex;gap:24px;align-items:center;justify-content:space-between}.brand{font-size:23px;font-weight:780;letter-spacing:-1px;text-decoration:none;color:var(--ink)}.brand span{color:var(--teal);font-size:11px;font-weight:650;letter-spacing:1.5px;margin-left:12px;text-transform:uppercase}.nav-links{display:flex;gap:23px;align-items:center;flex-wrap:wrap}.nav-links a{font-size:13px;font-weight:600;text-decoration:none;color:var(--muted)}.nav-links a[aria-current=page]{color:var(--teal)}.shell{max-width:1280px;margin:auto;padding:34px 32px 50px}.eyebrow{color:var(--teal);font-size:11px;letter-spacing:1.8px;font-weight:750;text-transform:uppercase}.page-intro{margin-bottom:28px}.page-intro h1{font-size:clamp(30px,4vw,47px);line-height:1.15;letter-spacing:-1.7px;font-weight:670;margin:9px 0 13px}.page-intro p{color:var(--muted);margin:0;max-width:780px}.intro-line{display:flex;align-items:flex-end;justify-content:space-between;gap:20px}.edition{font-size:12px;color:var(--muted);white-space:nowrap}.workspace{display:grid;grid-template-columns:270px minmax(0,1fr);gap:28px}.panel{background:var(--paper);border:1px solid var(--line);border-radius:var(--radius)}.institution-panel{align-self:start;padding:19px 14px;position:sticky;top:18px}.panel-heading{display:flex;justify-content:space-between;align-items:center;margin:0 5px 13px}.panel-heading h2{font-size:15px;margin:0}.count{font-size:11px;font-variant-numeric:tabular-nums;padding:2px 7px;background:var(--wash);border-radius:5px;color:var(--muted)}.field-label{display:block;font-size:12px;font-weight:650;color:var(--muted);margin-bottom:6px}input,select{width:100%;min-height:43px;background:#fff;border:1px solid #c7d4dc;border-radius:7px;padding:9px 11px;color:var(--ink);min-width:0}input::placeholder{color:#687b88}.institution-search{margin:0 5px 12px}.institution-options{max-height:530px;overflow-y:auto;scrollbar-width:thin}.institution-option{display:flex;width:100%;gap:8px;align-items:center;justify-content:space-between;border:0;border-radius:6px;background:transparent;color:var(--ink);padding:10px;text-align:left;font-size:12px;line-height:1.4;margin:2px 0}.institution-option span:first-child{overflow-wrap:anywhere}.institution-option:hover{background:var(--wash)}.institution-option[aria-pressed=true]{background:var(--soft);color:var(--teal);font-weight:700}.institution-option.other{border-top:1px solid var(--line);border-radius:0;margin-top:9px;padding-top:13px}.small-note{font-size:11px;color:var(--muted);line-height:1.6;margin:15px 6px 0}.search-panel{padding:20px;margin-bottom:18px}.search-row{display:grid;grid-template-columns:minmax(0,1fr) auto;gap:10px;align-items:end}.search-row input{min-height:47px}.button{display:inline-flex;align-items:center;justify-content:center;gap:8px;min-height:44px;border:1px solid var(--teal);border-radius:7px;padding:10px 19px;background:var(--teal);color:white;font-weight:650;font-size:13px;text-decoration:none}.button.secondary{background:#fff;color:var(--ink);border-color:var(--line)}.text-button{border:0;background:transparent;color:var(--teal);font-size:12px;text-decoration:underline;padding:6px}.filters{display:grid;grid-template-columns:1fr 1fr 1fr;gap:13px;margin-top:16px}.filter-bottom{display:flex;align-items:center;justify-content:space-between;gap:12px;margin-top:12px}.filter-bottom p{font-size:12px;margin:0;color:var(--muted)}.result-toolbar{display:flex;align-items:center;justify-content:space-between;gap:15px;margin:20px 0 12px}.result-toolbar h2{margin:0;font-size:14px;font-weight:650}.result-toolbar select{font-size:12px;min-height:34px;padding:6px 9px;width:auto;max-width:170px}.record{background:#fff;border:1px solid var(--line);border-radius:9px;padding:21px 23px;margin-bottom:12px;transition:border-color .15s}.record:hover{border-color:#8daab5}.record-top{display:flex;gap:7px;align-items:center;flex-wrap:wrap;margin-bottom:9px}.tag{font-size:10px;line-height:1.6;font-weight:650;letter-spacing:.25px;border-radius:4px;padding:3px 7px;background:var(--wash);color:var(--muted)}.tag.year{color:var(--teal);background:var(--soft)}.record h3{font-size:17px;font-weight:650;line-height:1.45;letter-spacing:-.2px;margin:0 0 8px}.record h3 a{color:var(--ink);text-decoration:none}.record h3 a:hover{text-decoration:underline}.authors,.journal{font-size:12px;color:var(--muted);margin:4px 0;overflow-wrap:anywhere}.journal{font-style:italic}.record-bottom{display:flex;align-items:flex-start;justify-content:space-between;gap:20px;border-top:1px solid #edf1f3;padding-top:12px;margin-top:13px}.institution-label{font-size:11px;color:var(--muted);max-width:70%;overflow-wrap:anywhere}.source-links{display:flex;gap:14px;flex-wrap:wrap;flex-shrink:0;font-size:12px;font-weight:650}.record details{font-size:11px;color:var(--muted);margin-top:10px}.record summary{cursor:pointer}.record details p{overflow-wrap:anywhere}.pagination{display:flex;justify-content:space-between;align-items:center;gap:14px;margin:22px 0}.pagination span{font-size:12px;color:var(--muted)}.empty{padding:36px;text-align:center;background:#fff;border:1px dashed #b8c9d1;border-radius:9px;color:var(--muted)}.notice{border-left:3px solid #89b3aa;padding:12px 17px;background:#edf4f2;font-size:12px;color:var(--muted);margin:18px 0}.site-footer{max-width:1280px;margin:0 auto;padding:24px 32px;border-top:1px solid var(--line);display:flex;justify-content:space-between;gap:20px;color:var(--muted);font-size:12px}.reg-grid{display:grid;grid-template-columns:1fr 1fr;gap:24px}.reg-card{padding:28px}.reg-card h2{font-size:25px;letter-spacing:-.6px;line-height:1.3;margin:8px 0 14px}.reg-card p{font-size:14px;color:var(--muted)}.facts{display:grid;grid-template-columns:1fr 1fr;gap:18px;padding:18px 0;border-block:1px solid var(--line);margin:20px 0}.facts dt{font-size:10px;text-transform:uppercase;letter-spacing:1px;color:var(--muted)}.facts dd{margin:4px 0 0;font-size:14px;font-weight:650}.document-link{display:flex;justify-content:space-between;align-items:flex-start;gap:15px;text-decoration:none;padding:14px 0;border-bottom:1px solid var(--line);font-size:13px;font-weight:650}.document-link small{font-size:10px;white-space:nowrap;font-weight:550;color:var(--muted)}.reg-card details{margin-top:20px;font-size:13px;color:var(--muted)}.reg-card summary{font-weight:650;cursor:pointer;color:var(--ink)}.wide-panel{padding:28px;margin-top:24px}.wide-panel h2{margin:0 0 12px;font-size:23px}.quick-grid{display:grid;grid-template-columns:repeat(3,1fr);gap:20px;margin:28px 0}.quick-card{padding:25px;display:flex;flex-direction:column;align-items:flex-start}.quick-card h2{font-size:21px;line-height:1.3;margin:10px 0}.quick-card p{font-size:13px;color:var(--muted);flex:1}.quick-card a{margin-top:12px}.section-heading{font-size:24px;letter-spacing:-.5px}.reading{max-width:880px}.reading h2{margin-top:36px}.reading p,.reading li{color:var(--muted)}.reading table{width:100%;border-collapse:collapse}.reading th,.reading td{border-bottom:1px solid var(--line);padding:12px;text-align:left}.reading .panel{padding:30px}
@media(max-width:950px){.workspace{grid-template-columns:225px minmax(0,1fr);gap:18px}.site-nav,.shell{padding-left:22px;padding-right:22px}.brand span{display:none}.record-bottom{display:block}.institution-label{max-width:none}.source-links{margin-top:8px}.reg-grid{grid-template-columns:1fr}.quick-grid{gap:13px}.quick-card{padding:20px}}
@media(max-width:680px){.site-nav{align-items:flex-start;flex-direction:column;gap:9px;padding:16px 18px}.nav-links{gap:16px}.shell{padding:25px 16px}.intro-line{display:block}.edition{margin-top:10px}.page-intro h1{letter-spacing:-1px}.workspace{display:flex;flex-direction:column;gap:16px}.institution-panel{position:static;width:100%}.institution-options{max-height:205px}.filters{grid-template-columns:1fr 1fr}.search-panel{padding:16px}.record{padding:18px}.search-row{grid-template-columns:minmax(0,1fr) auto}.search-row .button{padding:10px 14px}.site-footer{flex-direction:column;padding:22px 18px;gap:8px}.quick-grid{grid-template-columns:1fr}.reg-card,.wide-panel{padding:22px}.facts{gap:13px}.pagination .button{padding:8px 13px}.result-toolbar{align-items:flex-start}.small-note{margin-top:10px}.reading .panel{padding:20px}.reading{overflow-wrap:anywhere}.filter-bottom{align-items:flex-start}}
/* Veterinary overview: editorial metrics, comparable species bars and source records. */
.overview-intro{padding:8px 0 3px}.overview-actions{display:flex;flex-wrap:wrap;gap:10px;margin-top:22px}.overview-stats{display:grid;grid-template-columns:repeat(5,minmax(0,1fr));background:var(--paper);border:1px solid var(--line);border-radius:var(--radius);margin:26px 0;overflow:hidden}.overview-stat{display:flex;flex-direction:column;padding:21px 22px;text-decoration:none;color:var(--ink);border-right:1px solid var(--line);min-width:0}.overview-stat:last-child{border-right:0}.overview-stat:hover{background:var(--soft)}.overview-stat:focus-visible{outline-offset:-4px}.overview-stat strong{font-size:36px;font-weight:650;line-height:1.2;letter-spacing:-1.5px;font-variant-numeric:tabular-nums}.overview-stat>span{font-size:12px;font-weight:700;margin:9px 0 4px}.overview-stat small{font-size:11px;color:var(--muted);line-height:1.5}.overview-grid{display:grid;grid-template-columns:minmax(0,1fr) 310px;gap:24px;align-items:start}.species-panel{padding:27px}.overview-heading{display:flex;justify-content:space-between;align-items:center;gap:14px;flex-wrap:wrap}.overview-heading h2,.regulatory-overview h2{font-size:25px;line-height:1.25;letter-spacing:-.6px;margin:7px 0 0}.overview-caption{font-size:12px;color:var(--muted);line-height:1.65}.species-list{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));column-gap:28px;row-gap:4px;margin:20px 0}.species-item{display:flex;gap:10px;align-items:center;min-height:72px;border-bottom:1px solid var(--line);padding:12px 4px;color:var(--ink);text-decoration:none;min-width:0}.species-item:hover{background:var(--wash)}.species-icon{font-size:23px;flex-shrink:0;width:31px;text-align:center}.species-name{font-size:12px;font-weight:650;flex:1;min-width:0}.species-item>strong{font-size:21px;line-height:1;font-variant-numeric:tabular-nums;min-width:38px;text-align:right}.species-arrow{font-size:11px;color:var(--muted)}.species-track{display:block;height:4px;background:#e9eff0;border-radius:3px;margin-top:10px;overflow:hidden}.species-track>span{display:block;height:100%;background:var(--teal);border-radius:3px}.species-context .species-track>span{background:#607789}.overview-details{border-top:1px solid var(--line);padding-top:15px;margin-top:15px;font-size:12px;color:var(--muted)}.overview-details summary{cursor:pointer;color:var(--ink);font-weight:650}.regulatory-overview{padding:26px;background:#edf4f2;border-color:#c7dbd4}.regulatory-overview>p{font-size:12px;color:var(--muted)}.regulatory-overview>a:last-child{font-size:12px;font-weight:700}.milestone{display:flex;flex-direction:column;border-block-start:1px solid #c7dbd4;margin-top:19px;padding-top:16px;text-decoration:none;color:var(--ink)}.milestone>span{font-size:11px;font-weight:700}.milestone strong{font-size:37px;line-height:1.35;letter-spacing:-1px;font-weight:650}.milestone small{font-size:11px;color:var(--teal)}.milestone:hover small{text-decoration:underline}.clinical-highlight{display:grid;grid-template-columns:1fr 1fr;gap:38px;background:#153a47;color:#fff;padding:30px;border-radius:var(--radius);margin-top:26px}.clinical-highlight .eyebrow{color:#a7d9cb}.clinical-highlight h2{font-size:27px;line-height:1.25;letter-spacing:-.5px;margin:9px 0 16px}.clinical-highlight p{font-size:13px;color:#d6e3e7;line-height:1.7}.clinical-highlight a{font-size:12px;color:#c5f1e2}.clinical-stats{display:grid;grid-template-columns:1fr 1.6fr 1fr;gap:15px;margin:8px 0 22px}.clinical-stats dt{font-size:10px;color:#c6d9df}.clinical-stats dd{margin:7px 0 0;font-size:30px;line-height:1.35;font-weight:650;white-space:nowrap;letter-spacing:-.6px}.clinical-stats dd span{font-size:18px;color:#c6d9df}.clinical-highlight .clinical-limit{font-size:12px;border-top:1px solid #41606a;padding-top:18px}
@media(max-width:1050px){.overview-grid{grid-template-columns:minmax(0,1fr) 270px;gap:18px}.species-panel,.regulatory-overview{padding:22px}.species-list{column-gap:15px}.overview-stat{padding:18px 15px}.clinical-highlight{gap:25px}.clinical-stats{gap:10px}.clinical-stats dd{font-size:25px}}
@media(max-width:850px){.overview-grid{grid-template-columns:1fr}.overview-stats{grid-template-columns:repeat(3,minmax(0,1fr))}.overview-stat{border-bottom:1px solid var(--line)}.overview-stat:nth-child(3){border-right:0}.overview-stat:nth-child(n+4){border-bottom:0}.clinical-highlight{grid-template-columns:1fr;gap:14px}.clinical-stats{max-width:520px}.regulatory-overview{display:grid;grid-template-columns:1fr 1fr;column-gap:25px}.regulatory-overview>.eyebrow,.regulatory-overview>h2,.regulatory-overview>p,.regulatory-overview>a:last-child{grid-column:1/-1}}
@media(max-width:480px){.overview-stats{grid-template-columns:repeat(2,minmax(0,1fr))}.overview-stat:nth-child(3){border-right:1px solid var(--line)}.overview-stat:nth-child(even){border-right:0}.overview-stat:last-child{grid-column:1/-1;border-top:1px solid var(--line);border-right:0}.overview-stat strong{font-size:31px}.species-list{grid-template-columns:1fr;row-gap:0;margin:15px 0}.species-panel{padding:20px}.species-item{min-height:62px}.regulatory-overview{padding:20px;column-gap:15px}.clinical-highlight{padding:23px 20px}.clinical-stats{gap:8px;grid-template-columns:.8fr 1.6fr 1fr}.clinical-stats dd{font-size:25px}.clinical-stats dd span{font-size:15px}}
@media(prefers-reduced-motion:reduce){html{scroll-behavior:auto}*{transition:none!important}}